Add to ORKGMessenger RNA (mRNA) plays a critical role in cellular growth and development. However, there have been limited methods available to visualize endogenous mRNA in living cells with ease. We have designed RNA-based fluorescence "turn-on" probes that target mRNA by fusing an unstable form of Spinach with target-complementary sequences. These probes have been demonstrated to be selective, stable, and capable of targeting various mRNAs for live E. coli imaging
Fluorescence microscopy is a powerful quantitative technique able to resolve local concentrations an...
Noninvasive imaging of specific mRNAs in living subjects promises numerous biological and medical ap...
Transfer RNAs (tRNAs) perform essential tasks for all living cells. They are major components of the...
RNAs are dynamic molecules that orchestrate a breadth of processes for prokaryotes and eukaryotes in...
Fluorogenic RNA aptamers bind and activate the fluorescence of otherwise nonfluorescent dyes. Howeve...
Knowledge about ribonucleic acids (RNAs) and their roles has recently been expanded by extensive stu...
We show that the difficulties in imaging the dynamics of protein expression in live bacterial cells ...
Live cell RNA imaging using genetically encoded fluorescent labels is an important tool for monitori...
Imaging the behavior of RNA in a living cell is a powerful means for understanding RNA functions and...
BACKGROUND: Imaging the behavior of RNA in a living cell is a powerful means for understanding RNA f...
ability of Spinach to reveal the intracellular dy-namics of RNA in living cells. Wehave described a ...
Direct cellular imaging of the localization and dynamics of biomolecules helps to understand their f...
Fluorescence imaging of cellular components and biomolecules have given numerous insights in biomedi...
The transient nature of RNA has rendered it one of the more difficult biological targets for imaging...
Imaging products of gene expression in live cells will provide unique insights into the biology of c...
Fluorescence microscopy is a powerful quantitative technique able to resolve local concentrations an...
Noninvasive imaging of specific mRNAs in living subjects promises numerous biological and medical ap...
Transfer RNAs (tRNAs) perform essential tasks for all living cells. They are major components of the...
RNAs are dynamic molecules that orchestrate a breadth of processes for prokaryotes and eukaryotes in...
Fluorogenic RNA aptamers bind and activate the fluorescence of otherwise nonfluorescent dyes. Howeve...
Knowledge about ribonucleic acids (RNAs) and their roles has recently been expanded by extensive stu...
We show that the difficulties in imaging the dynamics of protein expression in live bacterial cells ...
Live cell RNA imaging using genetically encoded fluorescent labels is an important tool for monitori...
Imaging the behavior of RNA in a living cell is a powerful means for understanding RNA functions and...
BACKGROUND: Imaging the behavior of RNA in a living cell is a powerful means for understanding RNA f...
ability of Spinach to reveal the intracellular dy-namics of RNA in living cells. Wehave described a ...
Direct cellular imaging of the localization and dynamics of biomolecules helps to understand their f...
Fluorescence imaging of cellular components and biomolecules have given numerous insights in biomedi...
The transient nature of RNA has rendered it one of the more difficult biological targets for imaging...
Imaging products of gene expression in live cells will provide unique insights into the biology of c...
Fluorescence microscopy is a powerful quantitative technique able to resolve local concentrations an...
Noninvasive imaging of specific mRNAs in living subjects promises numerous biological and medical ap...
Transfer RNAs (tRNAs) perform essential tasks for all living cells. They are major components of the...